JAMA -- A Simplified Approach to the Management of Non-ST-Segment Elevation Acute Coronary Syndromes

While outcomes of controlled studies support a comprehensive approach in the management of patients with NSTE-ACS, many physicians perceive existing guidelines as lengthy and complex. After risk stratification to identify those patients most likely to benefit from an early invasive vs early conservative strategy, a comprehensive management plan can be assembled through an "ABCDE" approach. The elements of this include "A" for antiplatelet therapy, anticoagulation, angiotensin-converting enzyme inhibition, and angiotensin receptor blockade; "B" for beta-blockade and blood pressure control; "C" for cholesterol treatment and cigarette smoking cessation; "D" for diabetes management and diet; and "E" for exercise.

JAMA -- A Simplified Approach to the Management of Non-ST-Segment Elevation Acute Coronary Syndromes, January 19, 2005, Gluckman et al. 293 (3): 349